US Patent Issued to Navrogen on Sept. 16 for "Composition and methods for measuring antibody dynamics" (Pennsylvania Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,416,642, issued on Sept. 16, was assigned to Navrogen Inc. (Glen Mills, Pa.).

"Composition and methods for measuring antibody dynamics" was invented by Nicholas C. Nicolaides (Glen Mills, Pa.) and Luigi Grasso (Bryn Mawr, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Using protein structural probes one can identify tumor-induced or -produced (TIPS) factors that bind to therapeutic antibodies and change their dynamic structure, thereby negatively affecting their humoral immune functions as well as their pharmacologic activity. Using such protein structural probes and TIPS factors one can screen and identify inhibitors that can counter the binding o...