US Patent Issued to National University Corporation Hokkaido University on June 17 for "Modified adenovirus and medicine comprising same" (Japanese Inventor)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,793, issued on June 17, was assigned to National University Corporation Hokkaido University (Hokkaido, Japan).

"Modified adenovirus and medicine comprising same" was invented by Fumihiro Higashino (Sapporo, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "[Problem] The purpose of the present invention is to provide a modified adenovirus having a cytocidal activity on a target cell and high safety.[Solution] The present invention pertains to: a modified adenovirus which comprises an E1A gene, an enhancer sequence having a function of enhancing the expression of the E1A gene, and an AU-rich element introduced into the 3'-untranslated region of a v...