ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,921, issued on July 22, was assigned to National University Corporation Hokkaido University (Sapporo, Japan).
"Lipid nanoparticle" was invented by Yusuke Sato (Sapporo, Japan), Hideyoshi Harashima (Sapporo, Japan), Manabu Tokeshi (Sapporo, Japan) and Masatoshi Maeki (Sapporo, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention addresses the problem of providing a lipid nanoparticle in which a nucleic acid, etc., required in genome editing is encapsulated and which can be produced by an alcohol dilution method using flow channels and contributes to high genome editing efficiency. The present invention pertains to a lipid nanopa...