ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,636, issued on Nov. 25, was assigned to National University Corporation Hokkaido University (Hokkaido, Japan) and Mochida Pharmaceutical Co. Ltd. (Tokyo).

"Composition for treating intervertebral disc" was invented by Hideki Sudo (Hokkaido, Japan), Takeru Tsujimoto (Hokkaido, Japan), Norimasa Iwasaki (Hokkaido, Japan), Satoshi Shimizu (Tokyo) and Mitsuko Isaji (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a composition for filling the nucleus pulposus of an intervertebral disc, the composition containing a low endotoxin monovalent metal salt of alginic acid. The composition is applied to a nucleus pulposus site...