ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,453, issued on Sept. 30, was assigned to NATIONAL UNIVERSITY CORPORATION, IWATE UNIVERSITY (Morioka, Japan).
"Modified channelrhodopsin" was invented by Hiroshi Tomita (Morioka, Japan) and Eriko Sugano (Morioka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "An object of the present invention is to provide a modified channelrhodopsin having high ion permeability (photoreactivity). The solution is to substitute the third extracellular domain counted from the N-terminal side of three extracellular domains included in a Volvox carteri-derived channelrhodopsin by a corresponding extracellular domain of a Chlamydomonas reinhardtii-derived channelr...