US Patent Issued to National Taiwan University on Sept. 9 for "Gene therapy for AADC deficiency" (American, Taiwanese Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,409,235, issued on Sept. 9, was assigned to National Taiwan University (Taipei, Taiwan).

"Gene therapy for AADC deficiency" was invented by Mark Pykett (Cambridge, Mass.), Richard Thorn (Mendon, Mass.) and Wuh-Liang ("Paul") Hwu (Taipei, Taiwan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to compositions and methods for treating aromatic L-amino acid decarboxylase (AADC) deficiency. This invention includes a method of treating AADC deficiency in a pediatric subject, comprising the steps of: (a) providing a pharmaceutical formulation comprising an rAAV2-hAADC vector, (b) stereotactically delivering the pharmaceutical ...