ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,866, issued on July 8, was assigned to NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Tokyo) and KYORIN PHARMACEUTICAL Co. LTD. (Tokyo).

"Nucleic acid amplification method" was invented by Hidenori Nagai (Ikeda, Japan) and Satoru Iwanami (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a reciprocal-flow-type nucleic acid amplification method performing thermal cycling by reciprocating a sample liquid between a denaturation temperature zone and an elongation-annealing temperature zone with a connected microchannel including at least a curved channel corresponding to the denaturation temperature zone, a cu...