ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,016, issued on Sept. 16, was assigned to NANTONG UNIVERSITY (China).
"Preparation method for silk fibroin nerve graft fused with NT3" was invented by Yan Liu (Jiangsu, China), Mei Liu (Jiangsu, China), Xiaosong Gu (Jiangsu, China) and Tuchen Guan (Jiangsu, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "A silk fibroin nerve graft fused with NT3 and a preparation method therefor is provided. The method includes the steps of: synthesizing a gene fragment containing a silk fibroin light chain and NT-3, connecting the fragment to a pET-30 expression vector, and transferring the obtained recombinant expression vector into BL21 Escherichia coli to o...