US Patent Issued to Nano Vation Therapeutics on July 1 for "High sterol-containing lipid nanoparticles" (Canadian Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,343,405, issued on July 1, was assigned to Nano Vation Therapeutics Inc. (Vancouver, Canada).

"High sterol-containing lipid nanoparticles" was invented by Kevin An (Vancouver, Canada), Daniel Kurek (Vancouver, Canada), Jayesh Kulkarni (Vancouver, Canada) and Dominik Witzigmann (Vancouver, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a lipid nanoparticle comprising: a nucleic acid cargo molecule; sterol or a derivative thereof present at elevated content; neutral lipid; an ionizable lipid; and a hydrophilic polymer-lipid conjugate present at a content between 0.5 and 3 mol %, wherein each mol % content is relative ...