ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,294, issued on Dec. 16, was assigned to NANJING NUTRABUILDING BIO-TECH Co. LTD. (Nanjing, China).

"Methods for improving exercise performance and endurance thereof" was invented by Qiru Fan (Nanjing, China), Kylin Liao (Nanjing, China) and Mingru Wang (Nanjing, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods for improving exercise performance and endurance of a mammal, comprising administering to the mammal in need thereof a composition comprising dihydroberberine (DHB), or an analog or derivative thereof, and a physiologically acceptable carrier. DHB in the composition can serve as an antioxidant to defend red blood cells ...