ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,895, issued on Nov. 25, was assigned to MyNeuroCure Oy (Helsinki).
"C-terminal CDNF and MANF fragments, pharmaceutical compositions comprising same and uses thereof" was invented by Mart Saarma (Helsinki), Mikko Airavaara (Helsinki), Merja Voutilainen (Helsinki), Li Ying Yu (Helsinki) and Maria Lindahl (Helsinki).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a C-terminal CDNF fragment sequence or a sequence which has at least 80% homology or sequence identity to said sequence. The C-terminal CDNF fragment protects ER stressed neurons, motoneurons and dopaminergic neurons and the fragment is capable of penetrating neuro...