ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,953, issued on Nov. 4, was assigned to Muna Therapeutics ApS (Frederiksberg, Denmark).
"TREM2 modulators" was invented by Jakob Busch-Petersen (Frederiksberg, Denmark) and Gavin Whitlock (Sandwich, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds useful for modulating Triggering Receptor Expressed on Myeloid Cells-2 ("TREM2"). The invention also relates to the compounds for use in treatment of conditions related to loss of function of TREM2, such as neurodegenerative diseases, and to pharmaceutical compositions comprising the compounds."
The patent was filed on Jan. 3, 2025, under Application No...