ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,429, issued on Jan. 27, was assigned to Molecular Insight Pharmaceuticals Inc. (New York).
"Heterodimers of glutamic acid" was invented by John W. Babich (Cambridge, Mass.), Craig N. Zimmerman (Cambridge, Mass.) and Kevin P. Maresca (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of Formula (Ia) wherein R is a C6-C12 substituted or unsubstituted aryl, a C6-C12 substituted or unsubstituted heteroaryl, a C1-C6 substituted or unsubstituted alkyl or -NR'R', Q is C(O), O, NR', S, S(O)2, C(O)2 (CH2)p Y is C(O), O, NR', S, S(O)2, C(O)2, (CH2)p Z is H or C1-C4 alkyl, R' is H, C(O), S(O)2, C(O)2, a C6-C12 substituted or unsubstitut...