ALEXANDRIA, Va., March 12 -- United States Patent no. 12,246,030, issued on March 11, was assigned to ModernaTX Inc. (Cambridge, Mass.).
"Methods for therapeutic administration of messenger ribonucleic acid drugs" was invented by Stephen Hoge (Cambridge, Mass.), Tirtha Chakraborty (Cambridge, Mass.), Gilles Besin (Cambridge, Mass.) and Ruchi Jain (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure features methods of reducing or inhibiting an anti-drug antibody response in a subject, as well as methods of reducing or inhibiting unwanted immune cell activation in a subject to be treated with a messenger RNA (mRNA), comprising administering to the subject a mRNA, e.g., a chemically ...