ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,260, issued on Dec. 9, was assigned to ModernaTX Inc. (Cambridge, Mass.).
"Compositions and methods for delivery of agents" was invented by Gilles Besin (Brookline, Mass.), Stephen Hoge (Brookline, Mass.), Joseph Senn (Cambridge, Mass.), Kerry Benenato (Sudbury, Mass.) and Staci Sabnis (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile...