ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,347, issued on April 22, was assigned to Mitsubishi Chemical Corp. (Tokyo) and Toyama Prefectural University (Toyama, Japan).

"Method for producing 3-hydroxyisobutyric acid ester and methacrylic ester" was invented by Kenji Oki (Tokyo), Fujio Yu (Tokyo), Kozo Murao (Tokyo), Yasuhisa Asano (Toyama, Japan) and Fumihiro Motojima (Toyama, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "As a method for producing a 3-hydroxyisobutyric acid ester using a biocatalyst, a method for producing a 3-hydroxyisobutyric acid ester, including a step of allowing an alcohol or phenol to act on 3-hydroxyisobutyryl-CoA in the presence of alcohol acyltransferase to p...