ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,101, issued on Aug. 5, was assigned to MIRATI THERAPEUTICS INC. (Princeton, N.J.).
"Combination therapies" was invented by James Gail Christensen (San Diego), Lars Daniel Engstrom (Carlsbad, Calif.), Peter Olson (San Diego) and Ruth Wei Aranda (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SHP-2 inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I...