ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,055, issued on April 22, was assigned to MIRATI THERAPEUTICS INC. (Princeton, N.J.).
"Combination therapies" was invented by Jacob Haling (San Diego), John Michael Ketcham (Carlsbad, Calif.) and Shilpi Khare (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SOS1 inhibitor and a KRas G12C inhibitor, pharmaceutical compositions comprising a such compositions, k...