US Patent Issued to MICROSOFT TECHNOLOGY LICENSING on Sept. 30 for "De novo polynucleotide synthesis with substrate-bound polymerase" (Washington Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,659, issued on Sept. 30, was assigned to MICROSOFT TECHNOLOGY LICENSING LLC (Redmond, Wash.).

"De novo polynucleotide synthesis with substrate-bound polymerase" was invented by Bichlien Nguyen (Seattle), Jake Smith (Seattle) and Karin Strauss (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "De novo polynucleotide synthesis is performed with a substrate-bound polymerase. The polymerase is attached to a solid substrate such as a microelectrode array. The polymerase adds nucleotides to growing polynucleotides strands that are also attached to the solid substrate. Spatial control of polymerase activity is achieved by changing the rate of nucleot...