US Patent Issued to Microsoft Technology Licensing on Sept. 16 for "Regulation of DNA synthesis by nucleotides linked to protecting groups" (Washington Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,171, issued on Sept. 16, was assigned to Microsoft Technology Licensing LLC (Redmond, Wash.).

"Regulation of DNA synthesis by nucleotides linked to protecting groups" was invented by Karin Strauss (Seattle) and Bichlien Hoang Nguyen (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for DNA synthesis using protected nucleosides is disclosed. The nucleosides may be nucleoside triphosphates or nucleoside phosphoramidites with nucleobases attached to electrochemically-cleavable linkers. Removal of a protecting group by application of a voltage in solution triggers a cyclization reaction that cleaves the electrochemically-cleavable linker...