US Patent Issued to Microsoft Technology Licensing on Oct. 14 for "Multiplex assay for nucleic acid detection" (Washington Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,442,036, issued on Oct. 14, was assigned to Microsoft Technology Licensing LLC (Redmond, Wash.).

"Multiplex assay for nucleic acid detection" was invented by Yuan-Jyue Chen (Seattle), Karin Strauss (Seattle) and Bichlien H Nguyen (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "A multiplex assay for nucleic acid detection includes a substrate, a sample, and a fluorophore-labeled oligonucleotide. The substrate has a plurality of physically separated assay locations, each of which includes a nucleotide-targeting enzyme configured to cleave nucleic acids, a guide ribonucleic acid (gRNA), and a quencher-labeled oligonucleotide. A portion of the sampl...