US Patent Issued to Microsoft Technology Licensing on Feb. 25 for "Oligonucleotide assembly using pH based electrode controlled hybridization" (Washington Inventors)

ALEXANDRIA, Va., Feb. 26 -- United States Patent no. 12,234,502, issued on Feb. 25, was assigned to Microsoft Technology Licensing LLC (Redmond, Wash.).

"Oligonucleotide assembly using pH based electrode controlled hybridization" was invented by Yuan-Jyue Chen (Seattle), Bichlien Hoang Nguyen (Seattle), Karin Strauss (Seattle) and Jake Allen Smith (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Electrode controlled hybridization is used to change local pH and selectively assemble oligonucleotide complexes on the surface of a microelectrode array. The oligonucleotide complexes have sticky ends that provide locations for subsequent oligonucleotide complexes to hybridize. The order in which specific oli...