ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,086, issued on Aug. 12, was assigned to MICROSOFT TECHNOLOGY LICENSING LLC (Redmond, Wash.).
"Homopolymer primers for amplification of polynucleotides created by enzymatic synthesis" was invented by Yuan-Jyue Chen (Seattle) and Bichlien Nguyen (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure describes a technique for performing random access in a pool of polynucleotides by using one unique primer and one homopolymer primer to selectively amplify some but not all of the polynucleotides in the pool. The polynucleotides are synthesized by a template independent polymerase such as terminal deoxynucleotide transferase (TdT) rather ...