US Patent Issued to MGI Tech on Oct. 21 for "Controlled strand-displacement for paired end sequencing" (California Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,648, issued on Oct. 21, was assigned to MGI Tech Co. Ltd. (Shenzhen, China).

"Controlled strand-displacement for paired end sequencing" was invented by Radoje Drmanac (Los Altos Hills, Calif.) and Matthew J. Callow (San Jose, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This application relates to methods and compositions used for paired-end sequencing. The method comprises providing a DNA array comprising a surface immobilized with DNA concatemers. For each of the plurality of DNA concatemers on the array, the method comprises annealing first read primers to primer binding sites on the DNA concatemer, extending at least some of the first r...