ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,543, issued on Sept. 23, was assigned to MESA BIOTECH LLC (Carlsbad, Calif.).

"Oscillating amplification reaction for nucleic acids" was invented by Hong Cai (Los Alamos, N.M.) and Nathan J. Cobb (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "One embodiment of the present invention provides for a method for amplifying a template of nucleic acid target sequence contained in a sample. The method includes contacting the sample with an amplification reaction mixture containing a primer complementary to the template of nucleic acid target sequence. A temperature of the reaction is oscillated between an upper temperature and a lower tempera...