ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,782, issued on April 15, was assigned to MERZ PHARMA GmbH & Co. KGaA (Frankfurt am Main, Germany).

"Means and methods for the determination of the biological activity of neurotoxin polypeptides in cells" was invented by Cornelia Brunn (Frankfurt am Main, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention pertains to a method for directly determining the biological activity of a Neurotoxin polypeptide in cells, comprising the steps of: a) incubating cells susceptible to Neurotoxin intoxication with a Neurotoxin polypeptide for a time and under conditions which allow for the Neurotoxin polypeptide to exert its biological activity; b) ...