US Patent Issued to Merck Sharp & Dohme on Nov. 4 for "Compounds and methods of use thereof as antibacterial agents" (American, Chinese Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,933, issued on Nov. 4, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Compounds and methods of use thereof as antibacterial agents" was invented by Brendan M. Crowley (Collegeville, Pa.), Philippe Nantermet (Lansdale, Pa.), David Olsen (Lansdale, Pa.) and Takao Suzuki (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are dihydroisoxazole compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. Also disclosed are compositions which comprise at least one of these dihydroisoxazole compounds, methods for inhibiting growth of mycobacterial cells as well as a method of tr...