US Patent Issued to Merck Sharp & Dohme on May 13 for "Small molecule inhibitors of KRAS G12C mutant" (Massachusetts Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,208, issued on May 13, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Small molecule inhibitors of KRAS G12C mutant" was invented by Indu Bharathan (Somerville, Mass.), Symon Gathiaka (Waltham, Mass.), Yongxin Han (Needham, Mass.), Xiaoshen Ma (Boston), Ryan D. Otte (Natick, Mass.), David L. Sloman (Newton, Mass.), Thomas H. Graham (Somerville, Mass.), Timothy Henderson (Natick, Mass.), Elisabeth Hennessy (Weston, Mass.) and Anandan Palani (Needham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides compounds of Formula (I)or a pharmaceutically acceptable salt thereof, wherein W1, W2, Y, Z, M, L, Cy, Cz, R1, R2, R...