ALEXANDRIA, Va., June 12 -- United States Patent no. 12,295,998, issued on May 13, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).
"Enhancing immunogenicity of Streptococcus pneumoniae polysaccharide-protein conjugates" was invented by Julie M. Skinner (Phoenixville, Pa.) and Patrick McHugh (Pipersville, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides immunogenic compositions having one or more polysaccharide-protein conjugates in which one or more polysaccharides from Streptococcus pneumoniae bacterial capsules are conjugated to a carrier protein in an aprotic solvent such as dimethylsulfoxide (DMSO). The present invention also provides methods for providing an enha...