US Patent Issued to Merck Sharp & Dohme on Feb. 4 for "Pro drugs of PDE10 compounds" (New Jersey, Pennsylvania Inventors)

ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,215,101, issued on Feb. 4, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Pro drugs of PDE10 compounds" was invented by Sachin Mittal (Bridgewater, N.J.), Jason W. Skudlarek (Audubon, Pa.) and Izzat T. Raheem (Doylestown, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to pro drugs of 2-methyl-N-((5-methyl-1,3,4-thiadiazol-2-yl)methyl)-6-(((1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)pyrimidin-4-amine which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds ...