ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,552,826, issued on Feb. 17, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).
"PRMT5 inhibitors" was invented by Michelle Machacek (Belmont, Mass.), David Witter (Norfolk, Mass.), Chunhui Huang (Arlington, Mass.), Shuhei Kawamura (Cambridge, Mass.), Sebastian Schneider (Boston) and Murray Wan (Watertown, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a compound of formula (I) Formula (I) and the pharmaceutically acceptable salts, esters, and prodrugs thereof, are PRMT5 inhibitors. Also provided are methods of making compounds of formula (I), pharmaceutical compositions comprising compounds of formula (I), and m...