ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,403, issued on Dec. 16, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).
"Factor XIa inhibitors" was invented by John S. Debenham (Scotch Plains, N.J.), Cheng Zhu (Edison, N.J.), Amjad Ali (Freehold, N.J.), Sung-Sau So (Verona, N.J.) and Ying-Duo Gao (Middletown, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more compounds of Formula I compounds, and methods for using the compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibi...