ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,999, issued on May 27, was assigned to Merck Sharp & Dohme Corp. (Rahway, N.J.) and Amgen Inc. (Thousand Oaks, Calif.).

"Biomarkers for cancer therapeutics" was invented by Jennifer Lorraine Gansert (Simi Valley, Calif.), Abraham Antonio Anderson (Sherman Oaks, Calif.) and Kevin Gorski (Novato, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Biomarkers useful for identifying a variety of cancers that are responsive to treatment with a combination therapy comprising pembrolizumab, a pembrolizumab variant or an antigen-binding fragment thereof and talimogene laherparepvec are provided. Methods of treating cancers that are resistant to monotherap...