ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,800, issued on April 15, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.) and Adimab LLC (Lebanon, N.H.).
"Anti-coagulation factor XI antibodies" was invented by Zhu Chen (Warren, N.J.), Kenneth Ellsworth (Cranbury, N.J.), James Milligan (Sevierville, Tenn.), Elizabeth Oldham (Santa Clara, Calif.), Dietmar Seiffert (Lawrence Township, N.J.), Bianka Prinz (Lebanon, N.H.), Vaishnavi Ganti (Foster City, Calif.) and Mohammad Tabrizifard (Moranga, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation o...