US Patent Issued to Merck Patent on July 8 for "Viscosity reduction of highly concentrated protein formulations" (German, American Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,340, issued on July 8, was assigned to Merck Patent GmbH (Darmstadt, Germany).

"Viscosity reduction of highly concentrated protein formulations" was invented by Martin Zillmann (Shrewsbury, Mass.), Alexandra Krog (Bodenheim, Germany), Raphael Guebeli (Darmstadt, Germany), Tanja Henzler (Mannheim, Germany) and Christian Hildebrandt (Heppenheim, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compositions of highly concentrated protein formulations showing reduced viscosity. The contained proteins in the prepared formulations are stabilized against aggregation and denaturation and are thus sufficiently storage-st...