US Patent Issued to Merck Patent on July 1 for "Imidazolonylquinoline compounds and therapeutic uses thereof" (German Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,604, issued on July 1, was assigned to Merck Patent GmbH (Darmstadt, Germany).

"Imidazolonylquinoline compounds and therapeutic uses thereof" was invented by Thomas Fuchss (Bensheim-Auerbach, Germany), Axel Becker (Seeheim-Jugenheim, Germany), Holger Kubas (Bad Homburg, Germany) and Ulrich Graedler (Weinheim, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "Atropisomers, solid forms, salt forms, and deuterated derivatives of the ATM inhibitor 8-(1,3-Dimethyl-1H-pyrazol-4-yl)-1-(3-fluoro-5-methoxypyridin-4-yl)-7-methoxy-3-methyl-1,3-dihydroimidazo[4,5-c]quinolin-2-one as well as compositions thereof are provided. The stable atropisomers do not i...