US Patent Issued to MEMORIAL SLOAN-KETTERING CANCER CENTER on Dec. 30 for "Leucine zipper-based compositions and methods of use" (New York Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,498, issued on Dec. 30, was assigned to MEMORIAL SLOAN-KETTERING CANCER CENTER (New York).

"Leucine zipper-based compositions and methods of use" was invented by Scott E. James (New York), Marcel R. M. Van Den Brink (New York) and Lorenz Jahn (Brooklyn, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The presently disclosed subject matter provides compositions and systems for cell-based immunotherapy. In certain non-limiting embodiments, the system comprises a membrane-bound polypeptide and at least one soluble polypeptide that is capable of dimerizing with the membrane-bound polypeptide."

The patent was filed on Feb. 16, 2021, under Applicatio...