ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,802, issued on April 15, was assigned to MEMORIAL SLOAN KETTERING CANCER CENTER (New York).

"Compositions and methods for immunotherapy" was invented by Victor D. Fedorov (New York) and Michel Sadelain (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing an antigen recognizing receptor and an inhibitory chimeric antigen receptor (iCAR). Methods of using the immunoresponsive cell include those for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune re...