ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,240, issued on Nov. 4, was assigned to Melt & Marble AB (Gothenburg, Sweden).
"Fungal cell with improved protein production capacity" was invented by Mingtao Huang (Gothenburg, Sweden), Anastasia Krivoruchko (Gothenburg, Sweden), Florian David (Gothenburg, Sweden) and Jens Nielsen (Gothenburg, Sweden).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention related to the provision of genetically modified fungal cells, such as yeast cells with an improved ability for producing and secreting different recombinant proteins. The improved ability is obtained by disruption in intracellular transport between the Golgi and the endosome. In partic...