US Patent Issued to Medizinische Hochschule Hannover, Technische Universitat Braunschweig on Dec. 2 for "CAR for use in the treatment of HvG disease" (German Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,327, issued on Dec. 2, was assigned to Medizinische Hochschule Hannover (Hannover, Germany) and Technische Universitat Braunschweig (Braunschweig, Germany).

"CAR for use in the treatment of HvG disease" was invented by Elmar Jackel (Hannover, Germany), Fatih Noyan (Hannover, Germany) and Michael Hust (Hannover, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides an optimized and far potent chimeric antigen receptor for its use in the treatment of HvG disease in a patient having received a transplant, for use in suppressing the hosts immune response directed against the transplant. The fusion protein is adapted for use in sup...