US Patent Issued to MEDIVIR on Aug. 5 for "Protease inhibitors" (Swedish Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,209, issued on Aug. 5, was assigned to MEDIVIR AB (Huddinge, Sweden).

"Protease inhibitors" was invented by Lourdes Salvador Oden (Huddinge, Sweden), Magnus Nilsson (Huddinge, Sweden), Pia Kahnberg (Huddinge, Sweden), Bertil Samuelsson (Huddinge, Sweden) and Urszula Grabowska (Huddinge, Sweden).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of the formula II: wherein R1 and R2 are independently H, F or CH3; or R1 forms an ethynyl bond and R2 is H or C3-C6 cycloalkyl which is optionally substituted with one or two substituents independently selected from methyl, CF3, OMe or halo; R3 is C1-C3 alkyl or C3-C6 cycloalkyl, either of which is optio...