ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,654, issued on July 1, was assigned to MEDIGENE IMMUNOTHERAPIES GMBH (Planegg-Martinsried, Germany) and Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).
"Mage A4 T cell receptors" was invented by Christian Ellinger (Munich), Daniel Sommermeyer (Munich), Geoffrey Parsons (Jamaica Plain, Mass.) and Jasdeep Mann (Lake Forest Park, Wash.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an isolated T cell receptor (TCR) specific for MAGE-A4 and a polypeptide comprising a functional portion of the TCR. Further implicated are a multivalent TCR complex, a nucleic acid encoding a TCR, a cell expressing the TCR and a pharmaceuti...