ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,558, issued on July 8, was assigned to MEDICHEM S.A. (Sant Joan Despi, Spain).
"Process for the synthesis of lofexidine" was invented by I-Teng Montserrat Ng Choi (Girona, Spain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an improved process for the synthesis of lofexidine, or a pharmaceutically acceptable salt thereof, using an aluminium alkoxide as Lewis acid."
The patent was filed on April 16, 2021, under Application No. 17/913,915.
*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool...