ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,048, issued on March 25, was assigned to MEDIBEACON INC. (St. Louis).

"Method for non-invasive monitoring of fluorescent tracer agent with diffuse reflecting medium with time-varying optical properties" was invented by Kimberly Shultz (Mountain View, Calif.), Jennifer Keating (Mountain View, Calif.), Edward Solomon (Menlo Park, Calif.) and Kate Bechtel (Pleasant Hill, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of assessment of renal function by monitoring a time-varying fluorescence signal emitted from a fluorescent agent from within a diffuse reflecting medium with time-varying optical properties is provided that includes using...