ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,605, issued on Nov. 11, was assigned to Mayo Foundation for Medical Education and Research (Rochester, Minn.).
"Methods and materials for gender-dependent treatment of cardiovascular dysfunction" was invented by Jordan D. Miller (Rochester, Minn.), Maurice E. Enriquez-Sarano (Rochester, Minn.), Bin Zhang (Rochester, Minn.) and Carolyn Marie Roos (Rochester, Minn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This document provides methods and materials involved in treating cardiovascular conditions such as calcific aortic valve stenosis. For example, methods and materials for using sGC agonists or a combination of sGC agonists and PDE5A inhibitors ...