ALEXANDRIA, Va., June 16 -- United States Patent no. 12,305,168, issued on May 20, was assigned to Mayo Foundation for Medical Education and Research (Rochester, Minn.) and Iowa State University Research Foundation Inc. (Ames, Iowa).

"Materials and methods for efficient targeted knock in or gene replacement" was invented by Karl J. Clark (Rochester, Minn.), Stephen C. Ekker (Rochester, Minn.), Jeffrey Essner (Ames, Iowa), Jordan Michael Welker (Ames, Iowa), Maira Pedroso de Almeida (Ames, Iowa), Wesley Allen Wierson (Ames, Iowa) and Maura McGrail (Ames, Iowa).

According to the abstract* released by the U.S. Patent & Trademark Office: "Materials and methods for generating targeted knock ins and gene replacements with high precision and eff...