US Patent Issued to MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT on April 29 for "Fret-based method to measure seeding activity of misfolded protein species in biological samples" (German Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,287,344, issued on April 29, was assigned to MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (Berlin).

"Fret-based method to measure seeding activity of misfolded protein species in biological samples" was invented by Anne Ast (Berlin), Alexander Buntru (Hamburg, Germany) and Erich Wanker (Berlin).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for the quantification of seeding (trianglet50) of an amyloidogenic aggregate, methods for assessing the risk for development, predicting the onset or assessing the progression of a polyQ disease, and a method for identifying compounds that inhibit ...