US Patent Issued to Massachusetts Institute of Technology on Oct. 7 for "Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs" (Massachusetts, North Carolina Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,433,954, issued on Oct. 7, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs" was invented by Darrell J. Irvine (Arlington, Mass.), Karl Dane Wittrup (Boston), Naveen Mehta (Somerville, Mass.), Leyuan Ma (Brookline, Mass.) and Benjamin Cossette (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure features chimeric antigen receptor (CAR) ligands, methods for making the same, and immunomodulatory compositions comprising the CAR ligands. The disclosure als...