ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,433,946, issued on Oct. 7, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).

"Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof" was invented by Darrell J. Irvine (Arlington, Mass.), Karl Dane Wittrup (Boston), Tyson Moyer (Boston) and Yash Agarwal (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides immunomodulatory fusion proteins-metal hydroxide complexes comprising an immunomodulatory domain adsorbed to a metal hydroxide via ligand exchange. The disclosure also features compositions and methods of using the same, for example, to treat cancer."

The patent ...