ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,453,777, issued on Oct. 28, was assigned to Massachusetts Institute of Technology (Cambridge, Mass.).
"Uses of amphiphiles in immune cell therapy and compositions therefor" was invented by Darrell J. Irvine (Arlington, Mass.) and Peter C. Demuth (Medford, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for stimulating an immune response to a target cell population or a target tissue in a subject by administering to the subject a composition comprising an amphiphilic ligand conjugate. Such an amphiphilic ligand conjugate can comprise a lipid, one or more cargos (e.g., a CAR ligand, a chimeric cytokine receptor target, a c...